What Is Recombinant Collagen
Oct 21, 2024
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Recombinant collagen generally refers to recombinant human collagen. Recombinant humanized collagen is based on the original gene sequence of human skin type III collagen, which is optimized and selected for codon optimization and splicing and recombination of the part with strong water solubility and high biological activity, and a new recombinant humanized type III collagen sequence is obtained, which can be produced on a large scale by using biological fermentation technology. The fields of food and health care have broad application prospects.
There are many types of collagen, and the common types are type I., II., III., V., and XI. In normal skin tissue, collagen is mainly found in the form of type I and III collagen fibers. Type I collagen and type III collagen are closely related to the skin damage repair process and repair quality. Normal fetal skin type III collagen accounts for 60%, and with growth and development, type III collagen decreases and type I collagen increases. The collagen composition of adult skin is 80% type I and 20% type III. The mechanism of fetal scarless healing is due to the fetus's strong ability to synthesize type III collagen.
The role of recombinant collagen
The main role of recombinant human collagen is anti-aging and repair. The basic structure of recombinant humanized collagen is exactly the same as that of the human body, and it is optimized on this basis to improve the hydrophilicity and activity of collagen. Contains a large number of hydrophilic genes, has good film-forming properties, and keeps the stratum corneum of the skin hydrated. At the same time, its tropic guiding effect can guide epithelial cells to quickly enter the damaged area, effectively improve the speed of skin regeneration, shorten the wound healing time, and restore the skin barrier function.
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