Fish Collagen Peptides: The Natural Code For Protecting Heart And Brain Health, From Scientific Research Evidence To The Craftsmanship Inheritance Of Hunan Jiayi

Aug 11, 2025

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Cardiovascular diseases, as the number one threat to global health, nutritional intervention is becoming a focus of scientific attention. A review study published in the international authoritative journal "Marine Drugs" reveals that the active peptides in fish may have more diverse health potential than the Omega-3 we are familiar with! Hunan Jiayi Biotechnology is well aware of this. Its core product, Jiayi Fish collagen Peptide, is a natural guardian developed based on this scientific frontier.

 

I. Cutting-edge research Methods: Scientific exploration from the laboratory to the human body

The research team adopted a three-level verification system of "in vitro research - animal experiments - human clinical trials" to comprehensively evaluate the biological activity of Marine peptides. In vitro studies, by simulating digestive environments, it was confirmed that the proteolytic products of various fish and mollusks have antioxidant activity. Animal experiments were conducted using spontaneously hypertensive rats (SHR) and apolipoprotein E-deficient mice as models, and dietary variables were controlled to observe the long-term effects. Human trials, on the other hand, adopt gold standard designs such as randomized parallel intervention and double-blind control to ensure the reliability of the data.

 

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A. In vitro experiments: Simulating the human digestive process, it was confirmed that Marine proteins such as cod, tilapia, salmon, sardines, and shellfish can release specific peptides and amino acids (such as arginine and taurine) with ACE inhibitory activity (A key antihypertensive mechanism) and free radical scavenging ability through enzymatic hydrolysis.

 

B. Animal models: Long-term feeding experiments were conducted in spontaneous hypertension rats (SHR) and atherosclerotic model mice (ApoE-/-). The results show that animals that consume fish protein or specific hydrolysates:

 

Blood pressure was significantly reduced, and the effect was close to that of the antihypertensive drug captopril.

 

The atherosclerotic plaques are reduced by up to 24%.

 

The activity of antioxidant enzymes in the heart and liver is enhanced, and lipid peroxidation products (such as TBARS) are decreased.

The expression of <s:1> inflammatory markers (such as vascular cell adhesion molecule VCAM-1) decreased.

Some studies have shown a decrease in triglyceride levels.

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Clinical research (human trials) :

 

Randomized controlled trials (gold standard) : Participants were grouped and administered either Marine protein/peptides (such as cod, salmon peptides, fish protein supplements) or controls (placebos, other animal proteins).

 

Cross-design: The same subject receives different interventions successively to reduce the impact of individual differences.

 

Measurement indicators: blood pressure, blood lipids (cholesterol, triglycerides), oxidative stress markers (malondialdehyde MDA, antioxidant capacity), inflammatory factors (C-reactive protein CRP), gene expression, etc.

 

Animal samples: spontaneous hypertensive rats (SHR), apolipoprotein E-deficient mice (ApoE-/-, prone to atherosclerosis), Wistar rats, etc., with numbers ranging from a dozen to over a hundred.

 

Human sample

Healthy individuals: Overweight/obese individuals (most studied), and those with high normal blood pressure

High-risk/disease-prone groups: Patients with coronary heart disease, diabetes, and hypertension.

The sample size ranged from a dozen to several hundred (for example, the Nurses' Health Study followed over 80,000 women for 26 years).

Duration of long-term intervention: Most are 4 to 8 weeks, and some have long-term epidemiological observations for several years.

 

III. Key Research Data: The "Health Report Card" of Marine Peptides

A. Remarkable blood pressure-lowering effect:

 

1 gram of salmon peptide per day. After 4 weeks, the average systolic blood pressure decreased by 5 mmHg (from 140 to 135 mmHg).

Specific dipeptides (such as valinoacyl-tyrosine) can significantly lower blood pressure in patients with normal-high and mild hypertension.

The blood pressure of SHR rats that consumed cod protein was significantly lower than that of the control group that consumed casein.

Enhanced antioxidant capacity:

After overweight people consumed cod for 8 weeks, the oxidation products (malondialdehyde) decreased by 5%, and the total antioxidant capacity of serum was significantly enhanced.

SHR rats that consumed fish protein had reduced lipid peroxidation levels in the heart and liver and improved antioxidant status.

 

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C. Improving blood lipid and arterial health:

Some human studies have shown that replacing red meat with lean fish (such as cod) can lower triglyceride levels.

In animal experiments, mice in the cod/scallop protein group had 24% less atherosclerotic plaques and 19% less expression of inflammatory factors than those in the chicken protein group.

Epidemiology: Replacing one serving of red meat with one serving of fish every day reduces the risk of coronary heart disease in women by 30%.

 

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D. Anti-inflammatory effect:

 

In the cod protein group rats, inflammation subsided more rapidly, and the number of neutrophils at the injury site decreased significantly.

People with insulin resistance who consumed cod protein for 4 weeks saw a 24% decrease in C-reactive protein (CRP, a key inflammatory indicator), while those who consumed other animal proteins saw a 13% increase.

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Iv. Authoritative Research Conclusion: The "Heart and Brain Guardian Code" of Marine Peptides

Not limited to Omega-3: The protective effect of Marine fish on the cardiovascular system is not solely attributed to long-chain Omega-3 fatty acids. The bioactive peptides and amino acids (such as taurine, arginine, and glycine) released by its high-quality protein during digestion play a key role.

 

<S:1> lowers blood pressure: By inhibiting angiotensin-converting enzyme (ACE), regulating the renin-angiotensin system (RAAS), etc.

<s:1> Antioxidant: Eliminate free radicals, chelate pro-oxidation metals, and enhance the activity of endogenous antioxidant enzymes.

 

Nourishing blood vessels: Reducing endothelial inflammation, inhibiting foam cell formation, and slowing down the progression of atherosclerosis.Nourishing blood vessels: Reducing endothelial inflammation, inhibiting foam cell formation, and slowing down the progression of atherosclerosis.

profile.Regulating blood lipids: Some studies have shown that it can lower triglycerides and improve lipoprotein profile.

 

Great potential requires in-depth research: The preclinical (in vitro and in animals) evidence is abundant and positive, showing clear biological activity. The number of human clinical trials is relatively small and the results vary, but some high-quality studies (especially in the areas of blood pressure reduction and antioxidation) have shown significant and positive results. More rigorous and long-term human body research will be needed in the future.

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V. Application and Effectiveness: Jiayi Fish Collagen Peptide - The Choice of Science, the Key to Health

 

Hunan Jiayi Fish Collagen Peptide is precisely a model of transforming the above-mentioned cutting-edge scientific research achievements into daily health solutions:

1. Core technology, highly efficient activity release: Utilizing the patented "low-temperature enzymatic hydrolysis - molecular sieve filtration" dual process. Precisely cut the collagen from deep-sea fish (such as cod and salmon) to generate ultra-low molecular weight (300-1500 Da) collagen peptides. The small molecule characteristics make it more easily absorbed and utilized by the human body, directly reaching the target site, simulating the process of "digestion and release of bioactive peptides" in research, and maximizing the core functions such as ACE inhibition and antioxidation. This is precisely the molecular weight range that has been confirmed in the research to be the most easily absorbed by the human body and have the strongest biological activity, ensuring that each product carries the rigor of science.

 

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Scientific evidence, targeting heart and brain health: Product design directly points to core scientific research findings

Assist in regulating blood pressure: Rich in specific peptides with potential ACE inhibitory activity, it provides natural support for maintaining healthy blood pressure.Powerful antioxidant: Neutralize free radicals, reduce the damage of oxidative stress to vascular endothelium and heart cells, and protect the cardiovascular system from the source.

Nourishing blood vessels: It provides raw materials for the synthesis of collagen, which helps maintain the elasticity and integrity of blood vessel walls and combat arteriosclerosis.

 

Pure and safe, a reassuring choice: The raw materials are sourced from pure natural sea fish sources. The production process is strictly controlled, with zero additives, zero fat, and zero cholesterol, avoiding additional burdens. It is safe and gentle, suitable for long-term care.

Easy absorption and integration into daily life: With excellent water solubility, it can be easily dissolved in water, milk, porridge, soup, etc. Just one spoonful (about 10 grams) a day can conveniently supplement the scientifically proven Marine active essence.

Jiayi Fish collagen Peptide is not only a favorite of the skin, but also a natural guardian of the cardiovascular and cerebrovascular systems! It condenses the nourishing essence of deep-sea fish and cutting-edge biotechnology, based on scientific evidence, to provide you with health protection from the inside out. Choosing Jiayi means choosing to use the wisdom of nature and the power of science to lay a solid foundation for a vibrant life!

Act now and embark on your journey to heart and brain health! Let Jiayi Fish Collagen Peptide become an indispensable "peptide" for your healthy life!

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